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Lixte biotech holding, Inc. Uses as a drug discovery business. It has used biomarker technologies to identify—prepare of targets and develop novel combinations to attack those targets. The company focused on protein biochemistry avoidance used alone and in combination with cytotoxic agents X-Ray and immune system check of point blockers. It comprises two categories of compounds in various clinical and pre clinical develops stages . It has be developed two series of pharmacological. Active drug, inculcate the LB – 100 series. which consists of novel builds that cloud to be useful in the treatment of cancer and cardiovascular and metabolic diseases, and LB- 200 series for treatment of chronic genetic disorderliness such as a Phillippe Gaucher’s diseases as well as the cancer and neuro degenerative diseases. They companies was founded on 9,,August 2005, by the John s. Kovach and Robert B. Royd’s is headquarters in Pasadena, California.

LIXTE Biotechnology Properties, Inc

LIXTE is a drug discovery business that takes developed a unique, proprietary, best-in-class protein phosphatase inhibitor: LB-100, our lead clinical compound. LB-100 can be widely used as an anti-cancer go-between when used alone and in combination with standard anti-cancer treatments including cytotoxic drugs, radiation, and immune checkpoint blockers.

LB-100 Could Be A Game-Changer In Cancer Treatment.

Protein phosphatases are ubiquitous enzymes that regulate many signaling networks important for cell growth, division, and death. These enzymes, in particular protein phosphatase 2A (PP2A), have long been recognize as potentially important targets for anti-cancer drugs. However, due to their multifunctionality, their inhibition was thought to be too poisonous for medical use. Lixte has shown that this is not the case. In a Phase 1 clinical trial, LB-100, a PP2A inhibitor, was well tolerated at doses that result in significant tumor shrinkage (objective regression) and/or arrest of tumor progression in patients with progressive cancer.

LB-100 has been shown to inhibit a range of human cancers with abnormalities in PP2A function.

In extensive preclinical studies, LB-100, in combination with standard cytotoxic drugs and/or radiation therapy, increases the efficacy of these therapies against hematological cancers and solid tumors without increasing toxicity. Additionally, low doses of LB-100 have recently been shown to significantly increase the potency of PD-1 immune checkpoint blockade by activating cytotoxic T cells and CAR T cells. The addition of LB- 100 could be a breakthrough way to increase the effectiveness of cancer immunotherapy with anti-PD-1 and anti-CTLA-4 drugs.

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Lixt Stock Price

Lixte Biotech Hlds (LIXT)

0.7310 -0.0090 (-1.22%) 01/27/23 [NASDAQ]

0.7200 x 10 0.7700 x 7

POST-MARKET 0.7600 +0.0290 (+3.97%)

Previous Close0.7400


Avg Vol64,750

Stochastic %K86.66%

Weighted Alpha-47.64

5-Day Change+0.0210 (+2.96%)

52-Week Range

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